Redlin Art Center, Watertown

Interstate 29: South Dakota’s Cultural Corridor

Written by: TravelSouthDakota.com Staff Writer

Rich in history and art, eastern South Dakota offers endless opportunities for discovery. Just take a drive down I-29 to explore it all.

The main north-south corridor of eastern South Dakota, Interstate 29 passes through charming small towns filled with scenery and culture. Admire the art of Terry Redlin in Watertown, explore the many museums of Brookings, stroll the SculptureWalk in Sioux Falls and marvel at the rare instruments on display at the National Music Museum — just a few of the highlights you’ll see on I-29.

Sisseton

Enter South Dakota on Interstate 29 by heading south from North Dakota to the Sisseton area. 

Travel Tip: Held in Agency Village (about 7 miles south of Sisseton), the annual Sisseton-Wahpeton Oyate Wacipi is one of the longest-running powwows in the country.

Watertown

Drive south one hour (59 miles) to Watertown, a beautiful city with an abundance of outdoor recreation.

Travel Tip: While in Watertown, catch a show or take a fascinating tour of the recently renovated 1889 Goss Opera House.

Terry Redlin Art Center

Terry Redlin captured on canvas images of nature and small-town America. Enjoy more than 160 original oil paintings, shop exclusive gift shops or stroll the 30-acre Conservation Park.

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Mellette House

The Mellette House was once the home of South Dakota’s first governor, Arthur Calvin Mellette. Today visitors can tour the home to view the spectacular Italianate architecture and see what life was like in the late 1800s.

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Dark colored wolves at Bramble Park Zoo with visitors in the background watching in South Dakota.

Bramble Park Zoo

More than 800 animals and 130 species call the Bramble Park Zoo home. Highlights of the zoo include the Bear Crossing, Australian Adventure and interactive KidZoo.

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Brookings

Continue one hour south to Brookings. It’s the home of South Dakota State University, the largest university in South Dakota.

Travel Tip: Stop by for a scoop of ice cream made on-site at SDSU Dairy Bar.

South Dakota Art Museum

With more than 7,000 objects in its collection, the South Dakota Art Museum features rotating exhibits of Harvey Dunn paintings, Indigenous art, Marghab Linens and work by author/illustrator Paul Goble, as well as art from other regional, national and international artists.

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McCrory Gardens

McCrory Gardens features more than 25 acres of flowers, trees, shrubs and grasses, plus a 40-acre arboretum that provides a place for both scientific study and public exhibition. Pet-friendly and open daily from sunrise to sunset, the gardens are a great place to stop and smell the flowers!

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South Dakota Agricultural Heritage Museum

Located on the SDSU campus, the Agricultural Heritage Museum is dedicated to preserving South Dakota’s rural traditions and way of life. Exhibits feature farming technology, crops and livestock.

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De Smet

Made famous in the “Little House on the Prairie” books and TV series, De Smet celebrates the life of the Ingalls family in South Dakota. 

Note: De Smet is located 40 miles off the interstate, about a 45-minute drive west of Brookings. 

Ingalls Homestead

Visitors to the Ingalls Homestead can step into South Dakota’s pioneer past on the very land where Laura Ingalls Wilder’s family homesteaded, experiencing history through hands-on activities.

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Loftus Store

One of De Smet's first businesses, Laura Ingalls Wilder wrote about the Loftus Store in several of her stories. Visitors can still stop in the original store for “Little House on the Prairie” books, souvenirs and nostalgic treats.

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Sioux Falls

Enjoy the vibrant art, culture and cuisine of South Dakota’s largest city, Sioux Falls.

Travel Tip: Levitt at the Falls is a state-of-the-art outdoor music venue on the edges of Falls Park and downtown Sioux Falls. Each summer, the venue hosts 50 free concerts featuring a variety of artists and genres.

A metallic bear sculpture on the SculptureWalk in Sioux Falls, South Dakota.

SculptureWalk

With dozens of new sculptures installed every year, this massive public art installation turns downtown Sioux Falls into an open-air gallery. Stroll along Phillips Avenue to find your favorites.

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Good Earth State Park at Blood Run

More than a beautiful slice of nature, Good Earth State Park at Blood Run is rich in Indigenous heritage. View exhibits at the visitor center before wandering the trails.

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Vermillion

Only an hour south on Interstate 29, Vermillion sits atop a bluff of the last natural stretch of the Missouri River.

Travel Tip: Each June, Vermillion hosts the South Dakota Shakespeare Festival. Entertainment includes a full-length production, live music, food and more.

National Music Museum

Music lovers should plan a visit to the National Music Museum, which is home to a world-renowned collection of more than 15,000 musical instruments. A recent renovation and expansion has made it even more of a must-visit.

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W.H. Over Museum

Devoted to the collection, preservation, exhibition and interpretation of South Dakota’s history, the W.H. Over Museum features items representing natural history, inhabitants and the various cultural groups that have called South Dakota home.

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Yankton

While not directly on I-29, the city of Yankton is well worth a detour. Located 20 miles west of Vermillion, Yankton was the first capital of Dakota Territory, which included Wyoming, Montana and both Dakotas in the 1860s. See a replica of the Dakota Territorial Capitol and learn more state history at the Mead Museum.

Meridian Bridge

Meridian Bridge spans the Missouri National Recreational River, part of the National Park system. Visitors can walk, run or ride bikes on both levels of the bridge while enjoying a wonderful vantage point to look upon the river's wild and scenic waters.

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Gavins Point National Fish Hatchery & Aquarium

This hatchery has produced more than 5 billion fish for release in Midwestern waters. In the cool, softly lit surroundings of the aquarium, visitors become part of the aquatic environment while fish and turtles swim in 13 tanks.

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Lewis and Clark State Recreation Area

This popular park is located around Lewis and Clark Lake, one of four Missouri River reservoirs in South Dakota. Camp, hike, hit the water or just soak up the beauty and history of an area once explored by Lewis and Clark.

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More Stops Near Interstate 29 in South Dakota

  • South of Vermillion, Elk Point is where you’ll find a campground used by Lewis and Clark on their journey into South Dakota.
  • Pay a visit to North Sioux City, the farthest city south on Interstate 29 before crossing the border into Iowa.

Trip Planning Resources

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About the Author
TravelSouthDakota.com Staff WriterThis article was authored by Travel South Dakota's team of writers and editors. We’re passionate about sharing the best of South Dakota, whether it's exploring national and state parks, road-tripping, diving into local culture or uncovering hidden gems. Some of us grew up here, others got here as fast as we could — but we’re all on the lookout for the best spots to eat, stay and experience in the land of Great Faces, Great Places.